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DDB2 (DGR36085) Rabbit mAb

Product Name : DDB2 (DGR36085) Rabbit mAb

Cat.No.: db16320

Synonyms : XPE; DDBB; UV-DDB2

Application:

Reactivity : Human

Host species : Rabbit

Conjugation/Formulation:Un-conjugated

  • Background This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
  • Immunogen A synthetic peptide of human DDB2
  • Gene ID 1643
  • Swiss Prot Q92466
  • Synonyms XPE; DDBB; UV-DDB2
  • Reactivity Human
  • Application WB, IHC-P
  • Recommended dilution WB: 1:1000-1:5000
    IHC-P: 1:500-1:2000
  • Calculated MW 48 kDa
  • Observed MW 48 kDa
  • Host species Rabbit
  • Clonality Monoclonal
  • Clonality No. DGR36085
  • Isotype IgG
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
  • Western blot analysis of extracts from Raji cells using db16320 at 1:1000.
订购信息
  • Package Price (RMB)
  • 10μL 398
  • 20μL 698
  • 50μL 1398
  • 100μL 2398
  • 货期:现货
For research use only. Not intended for diagnostic.