DDB2 (DGR36085) Rabbit mAb
Product Name :
DDB2 (DGR36085) Rabbit mAb
Cat.No.:
db16320
Synonyms :
XPE; DDBB; UV-DDB2
Reactivity :
Human
Host species :
Rabbit
Conjugation/Formulation:Un-conjugated
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Background
This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
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Immunogen
A synthetic peptide of human DDB2
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Gene ID
1643
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Swiss Prot
Q92466
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Synonyms
XPE; DDBB; UV-DDB2
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Reactivity
Human
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Application
WB, IHC-P
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Recommended dilution
WB: 1:1000-1:5000
IHC-P: 1:500-1:2000
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Calculated MW
48 kDa
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Observed MW
48 kDa
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Host species
Rabbit
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Clonality
Monoclonal
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Clonality No.
DGR36085
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
×
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Western blot analysis of extracts from Raji cells using db16320 at 1:1000.
订购信息
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Package
Price (RMB)
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10μL
398
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20μL
698
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50μL
1398
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100μL
2398
- 货期:现货
For research use only. Not intended for diagnostic.