TAGLN Rabbit pAb - diagbio | 戴格生物

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TAGLN Rabbit pAb

db187

年底大促

Datasheet

Product Name : TAGLN Rabbit pAb

Cat.No.: db187

Synonyms : SM22; SMCC; TAGLN1; WS3-10; SM22-alpha

Application：

Reactivity : Human

Host species : Rabbit

Un-conjugated Un-conjugated Un-conjugated Un-conjugated Un-conjugated Un-conjugated

Background This gene encodes a shape change and transformation sensitive actin-binding protein which belongs to the calponin family. It is ubiquitously expressed in vascular and visceral smooth muscle, and is an early marker of smooth muscle differentiation. The encoded protein is thought to be involved in calcium-independent smooth muscle contraction. It acts as a tumor suppressor, and the loss of its expression is an early event in cell transformation and the development of some tumors, coinciding with cellular plasticity. The encoded protein has a domain architecture consisting of an N-terminal calponin homology (CH) domain and a C-terminal calponin-like (CLIK) domain. Mice with a knockout of the orthologous gene are viable and fertile but their vascular smooth muscle cells exhibit alterations in the distribution of the actin filament and changes in cytoskeletal organization. [provided by RefSeq, Aug 2017]
Immunogen A synthetic peptide of human TAGLN
Gene ID 6876
Swiss Prot Q01995
Synonyms SM22; SMCC; TAGLN1; WS3-10; SM22-alpha
Reactivity Human
Application WB, IHC
Recommended dilution WB: 1:1000-1:5000
IHC: 1:20-1:100
Calculated MW 23 kDa
Observed MW 23 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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