PRKAR2B Rabbit pAb - diagbio | 戴格生物

产品中心 Products Center

您当前的位置：

PRKAR2B Rabbit pAb

db26

年底大促

Datasheet

Product Name : PRKAR2B Rabbit pAb

Cat.No.: db26

Synonyms : PRKAR2; RII-BETA

Application：

WB
IHC
ICC/IF
IP

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Conjugation/Formulation：Un-conjugated

Un-conjugated Un-conjugated Un-conjugated Un-conjugated Un-conjugated Un-conjugated Un-conjugated Un-conjugated Un-conjugated Un-conjugated Un-conjugated Un-conjugated Un-conjugated Un-conjugated Un-conjugated Un-conjugated Un-conjugated Un-conjugated Un-conjugated Un-conjugated Un-conjugated Un-conjugated Un-conjugated Un-conjugated Un-conjugated Un-conjugated Un-conjugated Un-conjugated Un-conjugated Un-conjugated Un-conjugated Un-conjugated Un-conjugated Un-conjugated Un-conjugated Un-conjugated Un-conjugated Un-conjugated Un-conjugated Un-conjugated Un-conjugated

Background cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. This subunit has been shown to interact with and suppress the transcriptional activity of the cAMP responsive element binding protein 1 (CREB1) in activated T cells. Knockout studies in mice suggest that this subunit may play an important role in regulating energy balance and adiposity. The studies also suggest that this subunit may mediate the gene induction and cataleptic behavior induced by haloperidol. [provided by RefSeq, Jul 2008]
Immunogen A synthetic peptide of human PRKAR2B
Gene ID 5577
19088
24679
Swiss Prot P31323
P31324
P12369
Synonyms PRKAR2; RII-BETA
Reactivity Human, Mouse, Rat
Application WB, IHC, ICC/IF, IP
Recommended dilution WB: 1:1000
IHC: 1:1000
ICC/IF: 1:20
IP: 1:20
Calculated MW 46 kDa
Observed MW 46 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

订购信息

Package Price (RMB)
20μL 598
50μL 998
100μL 1798
货期：现货